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Symbol
Name
ID

Pfn3
profilin 3
MGI:2178800

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

reproductive system phenotype

abnormal sperm flagellum morphology

abnormal sperm connecting piece morphology

abnormal sperm midpiece morphology

abnormal sperm mitochondrial sheath morphology

necrospermia

oligozoospermia

abnormal sperm head morphology

abnormal acrosome morphology

abnormal acrosome assembly

abnormal proacrosomal vesicle fusion

globozoospermia

detached acrosome

abnormal sperm nucleus morphology

abnormal manchette assembly

decreased sperm progressive motility

asthenozoospermia

abnormal spermiogenesis

decreased litter size

reduced male fertility

impaired acrosome reaction

Availability

Mouse Genotype

Pfn3^em1Hsc/Pfn3^em1Hsc

*

Pfn3^em2Hsc/Pfn3^em2Hsc

*

Pfn3^em3Hsc/Pfn3^em3Hsc

*

Pfn3^em1Hsc/Pfn3⁺

*

Pfn3^em2Hsc/Pfn3⁺

*

Pfn3^em3Hsc/Pfn3⁺

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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